By John E. Johnson

The skill in which non-enveloped viruses penetrate mobile membranes in the course of telephone access stay poorly outlined. fresh findings point out numerous individuals of this workforce proportion a typical mechanism of membrane penetration during which the virus particle undergoes programmed conformational adjustments, resulting in capsid disassembly and liberate of small membrane-interacting peptides. a whole realizing of host telephone access via this minimum approach may help elucidate the mechanisms of non-enveloped virus membrane penetration more often than not

Show description

Read Online or Download Cell Entry by Non-Enveloped Viruses (Current Topics in Microbiology and Immunology, Volume 343) PDF

Best microbiology books

Plant Endocytosis (Plant Cell Monographs, Volume 1)

Endocytosis is a primary organic technique, that's conserved between all eukaryotes. it really is crucial not just for lots of physiological and signalling tactics but additionally for interactions among eukaryotic cells and pathogens or symbionts. This publication covers all features of endocytosis in either reduce and better crops, together with simple kinds of endocytosis, endocytic booths, and molecules excited by endocytic internalization and recycling in various plant telephone varieties.

Clinical Microbiology Made Ridiculously Simple, Edition 3

(Currently in 2004 revised printing) a quick, transparent, thorough, and hugely relaxing method of medical microbiology, brimming with mnemonics, humor, precis charts and illustrations, from AIDS to "flesh-eating micro organism" to ebola, mad cow affliction, hantavirus, anthrax, smallpox, botulism, and so forth. first-class Board assessment.

High-Yield Histology (High-Yield)

Now in its up to date 3rd version, High-Yield™ Histology extracts an important info on histology and offers it in a concise, uncluttered type to organize scholars for the USMLE. The e-book additionally serves as a superb direction overview, with illustrations and hundreds of thousands of assessment questions. High-Yield™ capability precisely that.

Handbook of Arbuscular Mycorrhizal Fungi

Arbuscular mycorrhizal fungi are obligate root symbionts that influence plant progress, productiveness and competitiveness. The e-book integrates key information regarding AMF thoughts, buildings and capabilities, and the hot category of Glomeromycota, together with themes approximately AMF background and evolution, AMF households, genus and species description, in addition to a compilation approximately a number of protocols to evaluate AMF and the way to spot them.

Additional resources for Cell Entry by Non-Enveloped Viruses (Current Topics in Microbiology and Immunology, Volume 343)

Sample text

4a) are distant from the location of the g amphipathic helix in FHV crystal structure, calcium site mutations affected the function of g and host cellular entry by FHV particles in a unique manner (Banerjee et al. 2010). The influence of the integrity of calcium binding sites on the biological function of g during virus entry is now being investigated. 4 Structure: Function Correlation of FHV Mutants A hybrid structural and biological approach was utilized recently to characterize the mutations in FHV capsid protein, and to provide a structural explanation of entryrelated biological phenomenon.

When the A B and C C P dimers moved as rigid bodies, they fit extremely well into the “floating” P domain density map. The fact that these structures fit well into the density strongly supports the contention that the gap between the P and S domains is due to either a large error in scale factor or contrast transfer function correction. There is, in fact, a handedness to the protruding domains themselves in that the P1 domain sticks out at an angle compared to the top P2 domain (Fig. 3). The hand that best accommodated this “twist” was used for modeling.

If the rabbits are infected by RHDV and survive, the appear to develop antibodies to the virus and are resistant to challenge later in life. Therefore, RHDV has a larger impact on the The Caliciviruses 25 local population if introduced after rabbits have bred and the young are old enough to be affected by the virus. The resistance observed in the natural population certainly suggests that adaptive immunity can control the infection. Indeed, vaccination of rabbits against RHDV infection has been accomplished through intramuscular injection of RHDV VLPs plus adjuvant (Laurent et al.

Download PDF sample

Rated 4.49 of 5 – based on 15 votes