By Maria Vallet-Regi

This e-book deals a special technique that hyperlinks the fabrics technology of bioceramics to scientific wishes and applications.

Providing a established account of this hugely energetic region of study, the publication studies the scientific purposes in bone tissue engineering, bone regeneration, joint alternative, drug-delivery structures and biomimetism, this booklet is a perfect source for fabrics scientists and engineers, in addition to for clinicians.

From the contents:

Part I Introduction

1. Bioceramics
2. Biomimetics

Part II Materials

3. Calcium Phosphate Bioceramics
4. Silica-based Ceramics: Glasses
5. Silica-based Ceramics: Mesoporous Silica
6. Alumina, Zirconia, and different Non-oxide Inert Bioceramics
7. Carbon-based fabrics in Biomedicine

Part III fabric Shaping

8. Cements
9. Bioceramic Coatings for scientific Implants
10. Scaffold Designing

Part IV examine on destiny Ceramics

11. Bone Biology and Regeneration
12. Ceramics for Drug Delivery
13. Ceramics for Gene Transfection
14. Ceramic Nanoparticles for melanoma Treatment

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Additional info for Bio-ceramics with clinical applications

Example text

Thus, taking into account that one of the main requirements for translational applications is a high throughput and automated method, which can also produce patient-specific constructs, then such an RP-based method can potentially be used to fabricate such customized tissues [9]. 8 shows the complete process in the design of a customized scaffold from RP techniques. 8 (a) Typical RP process chain. (b) Computed tomography (CT)-scanning of the built structures allows assessment of the accuracy of the process, by comparing the scan data to the design.

The capacity to adjust fiber size is one of the strengths of electrospinning, since fibers with diameters in the nanometer size range closely mimic the size scale of fibrous proteins found in the natural ECM, such as collagen. This ability of electrospun nanofibers to mimic the ECM is vital as previous studies have shown that both the size scale of the structure and the topography play important roles in cell proliferation and adhesion, respectively [13]. Also, non-woven fibrous mats comprised of nanofibers have a very high fraction of surface available to interact with cells, which makes them ideal for cell attachment.

Ceram. , 25, 375–383. 30. , Sanchez-Salcedo, S. and Vallet-Regí, M. (2007) Bioactive glass as precursor of designed –architecture scaffolds for tissue engineering. J. Biomed. Mater. , 81A, 224–232. 31. A. et al. (2004) Fabrication of low temperature macroporous hydroxyapatite scaffolds by foaming and hydrolysis of an alpha-TCP paste. Biomaterials, 25, 3671–3680. 32. , Jeon, O. et al. (2006) Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering. Biomaterials, 27, 1399–1409.

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