By Inge Scharrer, Wolfgang Schramm

This e-book comprises the contribution to the thirty fifth Hemophilia Symposium, Hamburg 2004. the most themes are epidemiology, danger of infections and inhibitors in hemophilia, persistent hemophilic synovitis and long term result of orthopedic therapy, laboratory diagnostics and pediatric hemostaseology. the quantity is rounded off by way of a number of unfastened papers and posters on hemophilia and hemorrhagic problems and inhibitors in hemophilia.

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Extra info for 35th Hemophilia Symposium Hamburg 2004: Epidemiology;Risk of Infections and Inhibitors in Hemophilia; Chronic lic Synovitis and Long-term Results of Orthopedic ... Hemostaseology;Free Lectures

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Schramm, H. Krebs 4. Ragni MV, Belle SH: Impact of human immunodeficiency virus infection on progression to end-stage liver disease in individuals with hemophilia and hepatitis C virus infection. J Infect Dis. 2001 Apr 1;183(7):1112–5. Epub 2001 Mar 01 5. Santagostino E, Colombo M, Rivi M, Rumi MG, Rocino A, Linari S, Mannucci PM; Study Group of the Association of Italian Hemophilia Centers: A 6-month versus a 12-month surveillance for hepatocellular carcinoma in 559 hemophiliacs infected with the hepatitis C virus.

Franke, D. Freund, W. Geib, R. Gerhardt, A. Gildberg, P. Gnad, M. Göbel, U. Gortner, L. Greinacher, A. Griesshammer, M. Großmann, R. Güldenring, H. Günther, G. Haberland, H. Hähling, D. Henze, G. Hesse, V. Hofmann, K. Holfeld, E. Holzhüter, H. Horneff, S. Horst, H. A. Hossfeld, K. Kabus, M. Kemkes-Matthes, B. Kentouche, K. Kiesewetter, H. Kirchmaier, M. Klamroth, R. Klare, M. Klarmann, D. Klinge, J. Knöfler, R. Koscielny, J. Krebs, H. Kreibich, U. Kretschmer, V. Kreuz, W. Kurnik, K. Kyank, U. Laws, H.

This was initially demonstrated in an animal model using susceptible sheep [6]. Two case reports of presumptive transmission of vCJD in humans were subsequently published in 2004 [7, 8], the second case report also being particularly important as this described the first case of vCJD in a subject heterozygous for methionine/valine at codon 129 in the prion gene and implying a wider susceptibility in the general population than previously reported. Of course, the fact that vCJD can be transmitted by a transfusion of whole blood does not automatically imply that fractionated plasma-derived products carry a similar risk.

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